GPAT Syllabus 2021: The exam date has been announced, it will be conducted on 22/ 27th February 2021. The syllabus for the Graduate Pharmacy Aptitude Test is prescribed by the National Testing Agency (NTA). Candidates appearing for the GPAT 2021 should have complete knowledge of the exam syllabus. It shall help you in the preparation process, as you can study the topics that require more attention and time. Thus, the subjects and topics are mentioned in this article. Further, you should solve as many question papers as possible. Those shall help you in having a better understanding of the exam pattern. For more details about the GPAT Syllabus 2021, exam pattern, important topics, and preparation tips, read further.

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  • GPAT 2021 will be conducted on 22/ 27th February 2021. Candidates should prepare well for the test as the exam date is near.

GPAT Syllabus 2021

The Syllabus of the Graduate Pharmacy Aptitude Test revolved around the topics of pharmaceutics. In addition, the exam pattern and syllabus in detail are provided below. The syllabus would probably be the same. However, if the syllabus is revised, then the same shall be updated here. Further, some of the important dates and events are mentioned in the table given below.



Commencement of Applications for GPAT 2021

23rd December 2020

Last date to fill Application Form

30th January 2021

Last date to upload documents and pay Application Fee

31st January 2021

Application Form Correction

02nd February 2021


22/ 27th February 2021

Check GPAT Registration Process

GPAT 2021 Exam Pattern

The exam pattern gives out all the details of the examination. Thus, along with the syllabus, it is important for students to be aware of the exam pattern. Further, the GPAT Exam Pattern 2021 as per the NTA guidelines is as follows:

  • Mode of the Exam: Online
  • Duration of the Exam: 3 Hours
  • Total No. of Questions: 125
  • Type of Questions: Multiple Choice Questions (MCQs)
  • Maximum Marks: 500
  • Further, each question carries 4 marks
  • In addition, negative marking is applicable, and thus for each incorrect answer, 1 mark gets deducted.

Detailed Syllabus of GPAT 2021

The important topics and subjects of the GPAT 2021 Syllabus are provided below. Candidates should ensure that they study these for good marks in the exam.



Physical Chemistry
  • Composition & physical states of matter
  • Refractive index
  • Solutions
  • Electrochemistry,
  • Kinetics
  • Colligative Properties
  • Thermodynamics
  • Ionic equilibrium
Physical Pharmacy
  • Buffer
  • Solubility
  • Matter, properties of matter
  • Viscosity and rheology
  • Surface and interfacial phenomenon
  • Dispersion systems
  • Complexation
  • Micromeritics and powder rheology
Organic Chemistry
  • General principles
  • Pericyclic reactions
  • Aromaticity & chemistry of aromatic compounds
  • Different classes of compounds
  • Amino acids & proteins
  • Different aromatic classes of compounds
  • Polycyclic aromatic hydrocarbons
  • Stereochemistry
  • Carbohydrates
  • Carbonyl Chemistry
  • Heterocyclic Chemistry
  • Protection & deprotection of groups
  • Bridged rings
  • Kinetic & thermodynamic control
Dispensing and Hospital Pharmacy
  • Introduction to laboratory equipment, weighing methodology, handling of prescriptions, labeling instructions for dispensed products
  • Posological calculations involved in the calculation of dosage for infants.
  • Study of current patent and proprietary products, generic products and selected brand products, indications, contraindications, adverse drug reactions, available dosage forms, and packing
  • Compounding and dispensing of following prescriptions
  • Reading and counselling of prescriptions from the clinical practice
  • Enlarging and reducing formula, displacement value
  • Preparations of formulations involving allegation, alcohol dilution, isotonic solution
  • General Pharmacology
  • Principles of toxicology
  • Drugs acting on the urinary system
  • Pharmacology of peripheral nervous system
  • Pharmacology of the cardiovascular system
  • Immunopharmacology
  • Drugs acting on Respiratory system
  • Pharmacology of Endocrine system
  • Neurohumoral transmission in the autonomic and central nervous system
  • Vitamins & Minerals
  • Pharmacology of central nervous System
  • Chemotherapy
  • Autacoids and their Antagonists
  • Pharmacology of drug acting on the gastrointestinal tract
  • Chronopharmacology
Pharmaceutical Chemistry
  • Pharmaceutical Inorganic Chemistry
  • Dentifrices, desensitizing agents, & anticaries agents
  • Pharmaceutical Impurities
  • Isotopes
  • Monographs
  • Medicinal Chemistry
  • Various classes of therapeutic agents
  • Different classes of therapeutic drugs
  • Therapeutic classes of drugs
  • Different classes of therapeutic drugs
Pharmaceutical Jurisprudence
  • Narcotic Drugs and Psychotropic Substances Act, and Rules thereunder
  • Factory Act
  • Shops and Establishment Act
  • Introduction to Intellectual Property Rights and Indian Patent Act 1970
  • An Introduction to Standard Institutions and Regulatory Authorities such as BIS, ASTM, ISO, TGA, USFDA, MHRA, ICH, WHO
  • Minimum Wages Act 1948
  • Prevention of Food Adulteration Act 1954 and Rules
  • Industrial Development and Regulation act 1951
  • Drugs and Magic Remedies (Objectionable Advertisements) Act 1954
  • Medicinal and Toilet Preparations (Excise Duties) Act 1955, Rules 1976
  • Historical background Drug legislation in India, Code of Ethics for Pharmacists
  • The Pharmacy Act 1948
  • Drugs and Cosmetics Act 1940, Rules 1945, including New Drug applications
  • Consumer Protection Act
  • Indian Pharmaceutical Industry- An Overview
  • Medical Termination of Pregnancy Act 1970 and Rules 1975
  • Prevention of Cruelty to Animals Act 1960
  • Drug (Price Control) Order
Pharmaceutical Management
  • Introduction to management
  • Inventory Management
  • Communication
  • Research Management
  • Human resource and development (HRD)
  • Planning and Forecasting
  • Organization
  • World trade organization (WTO) and trade-related intellectual property rights (TRIPS)
  • Standard institutions and regulatory authorities
  • GATT
  • Marketing Research
  • Leadership and motivation
  • Pharmacy Profession & Introduction to Pharmaceuticals
  • Introduction to the dosage form
  • Biological products
  • Pharmaceutical Plant, location, layout
  • Ophthalmic preparations
  • Preformulations
  • Packaging Materials
  • Cosmetics
  • Pilot plant scale-up techniques
  • Dosage Form Necessities and Additives
  • Powders
  • Sources of drug information
  • Tablets
  • Parenteral – product requiring sterile packaging
  • Suspensions
  • Emulsions
  • Suppositories
  • Stability of formulated products
  • Prolonged Action Pharmaceuticals
  • Novel Drug delivery system
  • GMP and Validation
  • Semisolids
  • Allopathic dosage form
  • Crude extract
  • Allergenic extract
  • Capsules
  • Liquids(solutions, syrups, elixirs, spirits, aromatic water, liquid for external uses)
  • Pharmaceutical Aerosols
Pharmaceutical Engineering
  • Material of constructions
  • Drying
  • Size reduction and size separation
  • Extraction
  • Mixing
  • Crystallization
  • Automated process control systems
  • Industrial hazards & safety precautions
  • Evaporation
  • Distillation
  • Fluid flow
  • Heat transfer
  • Filtration and Centrifugation
  • Dehumidification and humidity control
  • Refrigeration and air conditioning
  • Introductory Pharmacognosy
  • Classification of crude drugs
  • Plant products
  • Principles of plant classification
  • Pharmaceutical aids
  • Animal products
  • Traditional herbal drugs
  • Plants based industries and research institutes in India
  • Patents
  • Ayurvedic system of medicine
  • Homeopathic system of medicine
  • Toxic drugs
  • Enzymes
  • Natural pesticides and insecticides
  • Adulteration and evaluation of crude drugs
  • Quantitative microscopy
  • Factors influencing the quality of crude drugs
  • Techniques in microscopy
  • Introduction to phytoconstituents
  • Biogenetic pathways
  • Carbohydrates & lipids
  • Tannins
  • Volatile oils
  • Resinous drugs
  • Glycosides
  • Alkaloids
  • Extraction and Isolation Techniques
  • Phytopharmaceuticals
  • Quality control and standardization of herbal drugs
  • Herbal formulations
  • Worldwide trade of crude drugs and volatile oils
  • Herbal cosmetics
Human Anatomy and Physiology
  • Cell physiology
  • Endocrine Glands
  • Reproductive System
  • Gastrointestinal tract
  • Respiratory System
  • Autonomic nervous system
  • Cardiovascular system
  • Lymphatic system
  • The Blood
  • Sense organs
  • Skeletal System
  • Central Nervous system
  • Urinary System
Pharmaceutical Analysis
  • Importance of quality control in pharmacy
  • Acid-base titrations
  • Gravimetry
  • Extraction techniques
  • Potentiometry
  • Calibration
  • General principles of spectroscopy
  • Mass spectrometry
  • Polarography
  • Nephelometry & Turbidimetry
  • Ultraviolet-visible Spectrometry
  • Spectrofluorimetry
  • Flame photometry & atomic absorption spectrometry
  • Infrared spectrometry
  • Miscellaneous methods of analysis
  • Non-aqueous titrations
  • Oxidation-reduction titrations
  • Precipitation titrations
  • Complexometric titrations
  • Proton nuclear magnetic resonance spectrometry
  • Chromatography
  • Miscellaneous
Clinical Pharmacy and Therapeutics
  • Drug information services, Drug interactions
  • Drug interaction in pediatric and geriatric patients, drug treatment during pregnancy, lactation, and menstruation
  • Therapeutic drug monitoring, adverse drug reaction (ADR), types of ADR, Mechanism of ADR. Drug interaction, Monitoring, and reporting of ADR and its significance
  • Drug therapy for malignant disorders like leukemia, lymphoma and solid tumors
  • Age-related drug therapy: concept of posology, drug therapy for neonates, pediatrics, and geriatrics. Drugs used in pregnancy and lactation
  • Drug therapy in gastrointestinal, hepatic, renal, cardiovascular and Respiratory Disorders
  • Pharmacovigilance, Therapeutic drug monitoring, Neutraceuticals, essential drugs, and rational drug usage
  • General Principles, preparation, maintenance, analysis of observational records in Clinical Pharmacy
  • Drug therapy in infections of the respiratory system, urinary system, infective meningitis, TB, HIV, malaria, and filaria
  • The drug therapy for thyroid and parathyroid disorders, diabetes mellitus, menstrual cycle disorders, menopause, and male sexual dysfunction
  • Drug therapy for rheumatic, eye and skin disorders
  • Clinical trials, type, and phases of clinical trials, placebo, ethical and regulatory issues including Good clinical practice in clinical trials
  • Drug therapy for neurological and psychological disorders
  • Cell
  • Lipids
  • Enzymes
  • Nucleic acids
  • Vitamins
  • Biological oxidations & reductions
  • Carbohydrates
  • Proteins
  • Hereditary diseases
Biopharmaceutics and Pharmacokinetics
  • Bio-pharmaceutics
  • Bio-pharmaceutical statistics
  • Bio-availability & Bio-equivalence
  • Plant Cell and Tissue Culture
  • Fermentation Technology and Industrial Microbiology
  • Recombinant DNA Technology
  • Process and Applications
  • Animal Cell Culture
  • Biotechnology-Derived Products
  • Basic principles of cell injury and adaptation
  • Neoplastic diseases
  • Pathophysiology of common diseases
  • Laboratory tests for Liver function tests and kidney function tests
  • Immunopathology including amyloidosis
  • Infectious diseases
  • Basic mechanisms of inflammation and repair
  • Disorders of fluid, electrolyte, and acid-base balance
  • Disorders of homeostasis: white blood cells, lymphoid tissues, and red blood cells related diseases
  • Introduction to Microbiology
  • Microscopy and staining technique
  • Biology of Microorganisms
  • Microbial spoilage
  • Vaccines & Sera
  • Fungi and Viruses
  • Aseptic Technique
  • Sterilization & Disinfection
  • Microbial Assay

NTA GPAT Question Paper 2021

The students preparing for the exam should refer to GPAT Previous Year Question Papers. It shall help you in understanding the exam pattern better. Further, by solving papers, students can find out their weak areas as well. Therefore, after completing the syllabus, you should start solving the previous year’s papers. The question papers are available online or students can also get the books that contain papers. Further, it increases your chances of clearing the exam. Candidates should thus try and solve as many papers as possible. This question paper is made available in PDF format online on the NTA Official Website ( The students thus face no difficulty in downloading them.

Best Books for GPAT Preparation

The students should not refer to a lot of books as that may cause confusion. You should refer to one or two books for preparation. In addition, go for the books of authors who are known. However, for allowing you to easily choose the right book for yourself, we have listed some of the best books below.

Name of SubjectName of the BooksAuthors
PharmaceuticsThe Theory and Practice of Industrial PharmacyLiebermann and Lachman, Lackman, Remington, IP, Martin, NK Jain (for NDDS), GK Jani (For calculation)
Physical PharmacyMartin
Unit OperationPharmaceutical engineeringSubramanyam
PharmacologyReview of Pharmacology Lippincott William
Pharm-AnalysisSpectroscopy and Titration




PharmacognosyTrease and EvansWilliam.C.Evans
Medicinal ChemistryMedicinal and Pharmaceutical ChemistryHarkishan Singh
Organic chemistryOrganic ChemistryMorrison & Boyd
Natural Products ChemistryNatural ProductsO. P. Agrawal
Physical ChemistryPhysical ChemistryShishir Mittal
BiochemistryLippincott Wiliam Review of Biochemistry
PharmacologyPharma chemistryJerry March, I.L.Finar, Wilson
MicrobiologyMicrobiologyPelzar, Prescott
AnalysisSpectrometric Identification of Organic CompoundsSilverstein
JurisprudencePharmaceuticsN. K. Jain

GPAT Syllabus 2021 – Preparation Tips

Some of the preparation tips you must consider while preparing for GPAT 2021 are as follows:

  • The students should first gather complete information about the syllabus and exam pattern.
  • Then you should prepare a time-table for yourself, wherein you should mention all the topics and the time period within which you complete those. Further, this shall help you in knowing within how much time you can complete the syllabus.
  • Further, refer to only a few reference books and focus more on understanding the concepts well.
  • Make sure that you solve as many question papers or mock tests as possible. Candidates can solve online mock tests or else you can buy books that contain previous years’ papers.
  • In addition, don’t stress yourself out and do engage yourself in some physical activities or meditation as well.
  • Moreover, if you are finding it difficult to study yourself, then do look for a good institute. GPAT is a national level exam and you need to study hard to clear it.


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